Study opens new frontier for research into neurodevelopmental disorder

New research could pave a way for pharmacological interventions for a devastating brain abnormality, announces a recent press release by the University of Ottawa. An international team led by Armen Saghatelyan, a newly appointed Canada Research Chair at the University of Ottawa’s Faculty of Medicine has shed light on the underlying mechanisms of a mysterious brain abnormality […]

Identification of a previously unknown mechanism controlling the interaction between astrocytes and blood vessels in the brain

Title of publication : Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation. First author : Dr. Moises Freitas-Andrade A new publication from Dr. Baptiste Lacoste’s laboratory at University of Ottawa identifies a previously unknown mechanism controlling the interaction between astrocytes and blood vessels in the brain. Serving as bridges between neurons and blood vessels in the brain, astrocytes (a […]

With autism, the brain adapts to blood vessel problems by changing how it uses energy

Dr. Baptiste Lacoste wants to find out what’s going wrong with the blood vessels in the autistic brain. His team was the first to discover that these blood vessels don’t work properly in mouse models of autism, and there’s some cellular evidence that this happens in humans as well. Now, in a new study published in Cell Reports, the team […]

CIHR Faces of Health Research 2022: Dylan Smith

All humans require sleep daily to be physically and mentally healthy. Sleep is known to play a role in solidifying new memories and learning. However, researchers do not fully understand the processes in the brain that underlie the consolidation of newly acquired information and skills during sleep. With the support of a CIHR Fellowship, Dr. […]