Tag: Brain tumours

  • In a recent interview published in Best Health Canada magazine, Toronto brain surgeon Gelareh Zadeh discusses a new brain cancer therapy that could buy precious time for terminal patients.

    Working with a colleague at the Princess Margaret Cancer Centre, she developed a blood test that can not only detect brain cancer but reveal the type of tumour and its likelihood to recur. And in a recent, groundbreaking clinical trial at the UHN, she helped identify a new combination therapy that may give patients with glioblastoma months or even years longer to live. In the interview, Zadeh discusses neurosurgery’s razor-thin margin of error, how to predict the risk for brain tumours and the value of staying in the moment.

    Read the full interview in Best Health Canada magazine.

    This research was published in the high impact journal Nature Medicine (Open Access)

    Nassiri, F., Patil, V., Yefet, L.S. et al. Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nat Med 29, 1370–1378 (2023). https://doi.org/10.1038/s41591-023-02347-y

    Visit the Zadeh lab website to learn more about her groundbreaking research.

    Dr. Gelareh Zadeh is one of this year’s recipients of the 2023 Canada Gairdner Momentum Awards.


  • “For advancing the molecular and genomic understanding of brain tumours, leading to better ways of discriminating, classifying and managing brain tumour subtypes with potential to transform the clinical care of the disease.

    Gairdner Foundation

    Congratulations to Dr. Gelareh Zadeh, MD, PhD, FRCS(C), FAANS, who is the Dan Family Chair and Professor of Neurosurgery, University of Toronto on winning a 2023 Canada Gairdner Momentum Award!

    Dr. Gelareh Zadeh is a neurosurgeon and senior scientist who combines her in-depth clinical knowledge of brain cancer with clinical and translational research to improve the diagnosis and management of adult brain tumours.

    Dr. Zadeh’s research program applies advanced genomic and epigenomic profiling to further our understanding of the molecular regulators of brain tumours and to develop tools that can refine biomarkers of diagnosis to predict treatment responses and ultimately, improve patient outcomes.

    Learn more about Dr. Zadeh’s work on the Gairdner award website: https://www.gairdner.org/winner/gelareh-zadeh

    [su_youtube_advanced url=”https://www.youtube.com/watch?v=maMytT8NjAw” rel=”no” modestbranding=”yes”]